1. Infections & Radiation Damage

• Clostridial Myonecrosis (Gas Gangrene) – UHMS, ECHM, FDA, Medicare approved

• Necrotizing Soft Tissue Infections – UHMS, ECHM, FDA, Medicare approved

• Osteomyelitis (Refractory) – UHMS, ECHM, FDA, Medicare approved

• Osteoradionecrosis – UHMS, ECHM, FDA, Medicare approved

• Soft Tissue Radionecrosis – UHMS, ECHM, FDA, Medicare approved

• Cancer (Radiation Synergy) – UHMS, ECHM (For specific cases like osteoradionecrosis and soft tissue radionecrosis)

• Actinomycosis – ECHM (Under specific conditions)

• Chronic Sinusitis (CS) – Not approved

• Anaerobic Septicemia and Infection (Non-Clostridial) – Not approved

• Systemic Aerobic Infection – Not approved

2. Circulatory & Vascular Disorders

• Acute Peripheral Arterial Insufficiency – ECHM approved

• Diabetic Wounds – UHMS, ECHM, FDA, Medicare approved (For advanced cases)

• Severe Anemia – UHMS, ECHM, Medicare approved (When transfusions are unavailable)

• Arthritis (Rheumatoid, Osteoarthritis, Osteoarthrosis) – Not approved

• Chronic Fatigue Syndrome (CFS) – Not approved

• Chronic Pain Syndrome (CPS) – Not approved

• Pancreatitis (Acute & Chronic) – Not approved

• Mitochondrial Diseases (MTD) – Not approved

• Complex Regional Pain Syndrome (CRPS/RSD) – Not approved

• Peripheral Arterial Disease (PAD) – Not approved

• Peripheral Neuropathy (PN) – Not approved

• Chronic Peripheral Vascular Insufficiency – Not approved

• Cutaneous, Decubitus, and Stasis Ulcers – Not approved

3. Toxic Exposures & Poisoning

• Carbon Monoxide Poisoning – UHMS, ECHM, FDA, Medicare approved

• Cyanide Poisoning – UHMS, ECHM, FDA, Medicare approved

• Smoke Inhalation – UHMS, ECHM, FDA, Medicare approved (When related to CO or cyanide poisoning)

• COVID-19 (Long & Post) – Experimental, not approved

• Lyme Disease (LD) – Not supported or covered

• Toxic Mold Exposure & Other Toxins (Mycotoxicosis) – Not approved

• Sepsis (SEP) – Not approved

• Hepatic Necrosis – Not approved

• Aerobic Septicemia – Not approved

• Acute Thermal and Chemical Pulmonary Damage (e.g., Smoke Inhalation) – Covered under smoke inhalation

4. Trauma & Injury Recovery

• Air or Gas Embolism – UHMS, ECHM, FDA, Medicare approved

• Crush Injury, Compartment Syndrome & Other Acute Traumatic Ischemia – UHMS, ECHM, FDA, Medicare approved

• Decompression Sickness – UHMS, ECHM, FDA, Medicare approved

• Skin Grafts & Flaps (Compromised) – UHMS, ECHM, FDA, Medicare approved

• Thermal Burns – UHMS, ECHM, FDA, Medicare approved

• Bone Fractures (FX) – Not approved

• Tendon & Ligament Injuries – Not approved

• Athletic Performance & Recovery – Not approved

• Organ Transplantation (Preservation) – Not approved

• Organ Storage – Not approved

5. Hearing & Neurological Disorders

• Idiopathic Sudden Sensorineural Hearing Loss – UHMS, ECHM, FDA approved (With regional variation)

• Intracranial Abscess – UHMS, ECHM approved

• Cerebral Palsy – ECHM optional, not covered

• Autism Spectrum Disorder (ASD) – ECHM optional, not covered

• Migraine Headaches – ECHM evolving evidence, not widely covered

• Multiple Sclerosis (MS) – ECHM optional, not covered

• Tinnitus – ECHM evolving evidence, not covered

• Interstitial Cystitis (IC)

• Fibromyalgia (FM) – Not approved

• Post-Traumatic Stress Disorder (PTSD) – Evolving evidence, not approved

• Stroke Recovery (CVA) – Evolving evidence, not widely covered

• Traumatic Brain Injury (TBI) – ECHM optional, not widely covered unless in specific cases

• Cognitive Decline (MCI) – Not approved

• Bell's Palsy (BP) – Not explicitly covered, evolving evidence

• Alzheimer's Disease – Not covered

• Parkinson's Disease – Not covered

• Central Retinal Artery Occlusion (CRAO) – ECHM approved (under specific conditions), not widely covered by Medicare or FDA but recognized in emergency cases.

• Nonvascular Causes of Chronic Brain Syndrome (Pick’s, Alzheimer's, Korsakoff’s Disease) – Not approved

• Acute or Chronic Cerebral Vascular Insufficiency – Not approved

• Acute Cerebral Edema – Not approved

6. Autoimmune & Chronic Conditions

• Arthritic Diseases – Not approved

• Crohn’s Disease (CD) – Not approved

• Eczema (AD) – Not supported or covered

• Interstitial Cystitis (IC)

• Scleroderma (SSc) – Not covered

• Psoriasis (PSO) – Not covered

• Senility – Not approved

7. Reproductive Health & Wellness

• Erectile Dysfunction (ED) – Not covered

• Fertility (Men & Women) – Not covered

8. Addiction & Recovery

• Drug & Alcohol Recovery – Not covered

9. Cardiovascular & Pulmonary Disorders (New Category for Missing Conditions)

• Myocardial Infarction – Not approved

• Cardiogenic Shock – Not approved

• Pulmonary Emphysema – Not approved

• Sickle Cell Anemia – Not approved

• Exceptional Blood Loss Anemia – UHMS, Medicare approved

10. Cognitive Enhancement/Neuroplasticity

• HBOT and Brain Health: Ongoing research explores HBOT's role in enhancing cognitive functions such as memory, focus, and learning. Animal studies and early-stage human research suggest HBOT may promote neuroplasticity, potentially supporting accelerated learning, memory improvement, and enhanced concentration.

• Intelligence and Learning: Although speculative, some studies hint that increased oxygen delivery could help improve mental clarity, focus, and cognitive performance in sustained attention tasks. Biohackers are exploring HBOT as a cognitive enhancer, though its nootropic effects are not yet scientifically validated.

• Supporting Study: Small-scale research on mild cognitive impairment (MCI) has shown slight improvements in cognitive function, opening a potential area for future research.

11. Recovery from Mental Fatigue & Stress

• Mental Burnout & Stress Recovery: Some anecdotal reports and early studies suggest that HBOT may help alleviate mental fatigue and burnout by improving oxygen delivery, promoting brain recovery from stress-related deficits, and enhancing mental resilience.

12. Sports Performance Recovery & Focus

• Enhanced Focus and Reaction Time: Some athletes use HBOT to recover from physical fatigue while maintaining mental sharpness during training and competition. Speculatively, HBOT could improve focus, reaction time, and decision-making in academic or mental performance tasks as well.

13. Anti-Aging / Longevity

• Age-Related Cognitive Decline: HBOT is being studied for its potential to delay the onset of cognitive decline in older adults, which may extend to improving concentration and cognitive function across all age groups. Improved oxygenation may slow the general decline in cognitive performance.

• Cellular Repair & Telomere Lengthening: Research speculates that HBOT may promote cellular repair and lengthen telomeres, which could theoretically extend lifespan and improve brain health.

14. Mental Health Disorders (Broader Scope)

• Depression, Anxiety, ADHD: Ongoing research explores whether HBOT can alleviate symptoms of depression, anxiety, and ADHD by improving oxygen delivery and neural function, though current findings are preliminary.

15. Sleep Disorders & Optimization

• Improved Sleep Quality: Practitioners suggest that HBOT may enhance sleep quality by improving oxygen delivery to the brain and aiding recovery during sleep cycles, potentially benefiting individuals with insomnia, sleep apnea, or other sleep disorders.

• Jet Lag Recovery: Athletes and business executives have used HBOT to recover from jet lag, helping to recalibrate the body's internal clock and alleviate travel-related fatigue.

16. Traumatic Psychological Injuries

• Emotional Trauma Recovery: Beyond PTSD, researchers are examining HBOT’s broader applications for treating psychological trauma and acute stress disorders. The increased oxygen supply may aid in neuroplasticity, supporting faster recovery from trauma-related brain changes.

17. Autism & Neurodevelopmental Disorders

• Autism Learning & Social Functioning: Research is investigating HBOT’s potential to improve learning abilities and social functioning in children with Autism Spectrum Disorder (ASD) by enhancing neural connectivity. Some parents and practitioners report learning benefits for ASD patients, although this remains speculative.

• Learning Disabilities (Dyslexia, ADHD): Emerging theories suggest that HBOT may help children and adults with learning disabilities, such as dyslexia and ADHD, by improving cognitive processing through enhanced oxygenation.

18. Post-Surgical Cognitive Function Recovery

• Post-Anesthesia Brain Fog: HBOT may help patients recover from post-anesthesia cognitive deficits (brain fog), particularly in elderly patients or those recovering from surgery, by promoting faster brain recovery.

19. Mood & Emotional Balance

• Depression & Anxiety: Preliminary studies are exploring whether HBOT can help balance neurotransmitters and reduce symptoms of chronic stress, anxiety, and bipolar disorder. Practitioners report that patients experience greater mental clarity and emotional stability after multiple HBOT sessions.

20. Regenerative Medicine & Stem Cell Activation

• Stem Cell Activation: Research is examining whether HBOT can promote the release and mobilization of stem cells, which may enhance the body’s regenerative processes, offering potential applications in age-related degeneration, injuries, and chronic diseases.

21. Optimized Learning & Memory Formation

• Memory Athletes: Competitive memory athletes may benefit from HBOT’s effects on memory formation and recall, as improved brain oxygenation could optimize learning and retention. Students may also find HBOT helpful in boosting focus and memory recall for exam preparation.

22. Aesthetic & Beauty Applications

• Skin Rejuvenation & Collagen Production: HBOT is being explored for aesthetic purposes, such as promoting skin rejuvenation, improving skin elasticity, tone, and hydration, and potentially stimulating collagen production. It may also aid in hair growth by improving blood flow to hair follicles.

23. General Health Maintenance (Biohacking)

• General Immune Boost: Enthusiasts speculate that HBOT may boost immune function by enhancing the efficiency of oxygen-dependent immune cells. Although largely anecdotal, biohackers use HBOT to optimize performance, energy levels, and overall well-being.

24. Regenerative Dentistry & Oral Health

• Gum Disease & Oral Surgery Recovery: HBOT is gaining interest in dentistry for accelerating recovery from oral surgeries and treating severe gum disease. Enhanced oxygenation could promote healing in areas like the mouth, which are traditionally difficult to treat.